Sam Maddox, a troubled girl whose father committed suicide, has earned a reputation at her high school for being a bit promiscuous. When Sam begins seeing brilliant, MIT-bound Henry Sinclair, the two opposites really attract. Although Sam doesn't realize it, Henry is in the grip of an insane romantic obsession, and he will kill anyone who tries to put an end to his star-crossed - and increasingly deadly - romance.

In a small town in 1967, plucky young sissy Phillip is about to celebrate his birthday at the beach cottage owned by his best friend Stan. All of Phillip's friends are gathered for the festivities, including Stan's hunky-but-impulsive boyfriend Billy, Billy's shy, nerdy cousin Joseph, and Randall, the chain-smoking, bitter queen of the bunch. Meanwhile, a horde of libidinous gay men - turned into ravenous flesh-eating zombies by toxic mosquitoes at a cruisy highway rest stop - are making their way towards our oblivious celebrants, eating every man in their path. With body parts washing up on shore and party guests disappearing, our heroes must find a way to stop the zombie onslaught. Will Stan keep the rotting corpses out of his spotless home? Will Joseph work up the courage to declare his love for Phillip? Will Billy keep it in his pants long enough to stay alive? Will Phillip's cheating boyfriend make it to the party - and if so...